Figure 3. Single-particles cryo-EM structures of KimA potassium channel determined using SMALP technology.
(A) Single-particle cryo-EM structure of KimA potassium channel dimer (PDB: 6S3K), in the structure, even without detergent, no lipids were resolved in the transmembrane domain. Transmembrane region analysis using PPM server showing the transmembrane domain of the dimer composed of two tilted subunits. (B) Transmembrane region analysis of a single subunit of KimA potassium channel dimer (PDB: 6S3K). The transmembrane domain region calculated from the monomer is drastically different from that of the KimA dimer.