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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Am Heart J. 2020 Jul 24;229:110–117. doi: 10.1016/j.ahj.2020.07.012

Table 2:

Baseline characteristics by evidence of use of OACs among privately insured members with atrial fibrillation and CHA2DS2-VASC scores ≥2

Patients Not Using an OAC at Baseline* Patients Using an OAC at Baseline* P-value
Totals 43,826 76,696
N % N %
Age <0.0001
<30–44 150 0.3 158 0.2

45–64
3,375 7.7 6,407 8.4

65–74
13,343 30.4 24,059 31.4

75–80+
26,958 61.5 46,072 60.1
Female sex 21,171 48 35,244 46 <0.0001
Geographic Region <0.0001
New England 1,245 3 3,602 5

Mid-Atlantic
1,879 4 4,374 6

South-Atlantic
23,488 54 42,155 55

Midwest
12,204 28 17,190 22

Mountain
2,074 5 3,725 5

Pacific
2,921 7 5,635 7

Unknown
15 0 15 0
Anemia 22,702 52 36,565 48 <0.0001
Hypertension 41,247 94 73,342 96 <0.0001
Diabetes 17,172 39 33,325 44 <0.0001
Peripheral vascular disease 13,253 30 22,971 30 0.29
Prior cerebrovascular or thromboembolic event 14,127 32 23,472 31 <0.0001
Prior cerebrovascular event 9,075 21 18,214 24 <0.0001
Stroke or TIA 7,493 17 15,149 20 <0.0001
TIA 5,850 13 11,603 15 <0.0001
Stroke 3,547 8 7,969 10 <0.0001
Heart failure 17,694 40 36,468 48 <0.0001
Kidney disease 3,328 8 5,193 7 <0.0001
Dialysis 1,498 3 2,398 3 0.006
History of MI 5,405 12 8,170 11 <0.0001
History of CABG 6,529 15 10,639 14 <0.0001
CHA2DS2-VASC <0.0001
0–1 0 0 0 0

2
5,264 12 6,940 9

3
8,240 19 13,775 18

4
10,179 23 18,126 24

5
8,620 20 16,158 21

6
5,798 13 11,022 14

7
3,374 8 6,441 8

8
1,809 4 3,342 4

9
542 1 892 1

Mean
5 NA 5 NA >0.99

SD
1.7 NA 1.6 NA
Atria score <0.0001
<= 3 (low) 20,852 48 39,238 51

4 (intermediate)
6,021 14 10,860 14

5 (high)
16,953 39 26,598 35
Hospitalizations in the prior 6 months 0.15
0 37,382 85 65,791 86

1
5,007 11 8,476 11

2
1,032 2.4 1,743 2.3

≥3
405 0.9 686 0.9
*

OAC use at baseline was defined as any OAC use in the prior 12 months.