TABLE 2.

New-Generation (Q-NRG) IC measurement guidelines

✓	Patient not agitated and sedation and analgesia drug doses stable, neuromuscular blockade are acceptable for measures and has minimal effect on REE measure
✓	Ideally, for best measures: Patient temperature should not change by >1 °C Patient ABG should not change by pH >0.1, hour before IC
✓	Establish FIO2 of <70%, the maximum expected for clinical accuracy for new QNRG Device accuracy
✓	Preferred PEEP: ≤16 cm H2O, and peak airway pressure: ≤30 cm H2O
✓	No air leaks (ie, no chest tubes) and patient has stable ventilator settings for ≥30 minutes
✓	Perform IC 4 hours before/after CRRT use. Perform IC before or >4 hours after intermittent hemodialysis
✓	Ideally, wait ≥60 minutes after painful procedure or changes in catecholamine, sedative, or analgesic dose

Recommendations taken from Oshima et al,⁶ Kaviani et al,³¹ and Uehara et al³⁸ and QNRG operating manual (COSMED, Inc).

ABG, arterial blood gas; CRRT, continuous renal replacement therapy; IC, indirect calorimetry; FIO₂, fraction of inspired oxygen; PEEP, positive end-expiratory pressure; REE, resting energy expenditure.