Consensus statements. Consensus statements.
Oral food provocation (especially double-blind placebo-controlled) is the gold standard in the diagnosis of IgE-mediated food allergy. | Strong consensus |
If there is evidence of augmentation factors, these should be taken into account during provocation. | Strong consensus |
Food provocations should be performed when indicated to confirm or exclude allergy. Provocation provides the basis for a safe food ingestion, allows counseling regarding appropriate allergen avoidance, and provides an assessment of the risk for severe reactions (anaphylaxis). |
Consensus |
A negative oral food provocation should be followed by repetitive cumulative administration of the tested food in an age- and daily-adapted amount no earlier than the next day to confirm clinical tolerance. | Strong consensus |
Oral food provocations should be performed in specialized facilities where emergency measures are immediately available. In addition, for provocation with a high risk of severe allergic reactions, intensive medical support should be available. | Strong consensus |