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. 2021 Jul 8;5:195–243. doi: 10.5414/ALX02257E

Table 13. Barriers for the evaluation of specific IgE results.

Technical and methodological errors (reasons for false-positive and false-negative results)
Poor quality of reagents (e.g., allergen extracts or their extraction, coupling and stability) laboratory errors
Interpretation errors (reasons for clinically irrelevant results)
Strongly increased total IgE with multiple sensitizations high sensitivity of detection cross-reactive IgE antibodies

IgE = Immunoglobulin E.