| Allergen |
Molecule (protein, e.g., major allergen Gad c 1 from cod, rarely carbohydrate component) that can trigger an allergic immune response. |
| Allergen extract |
Mixture of allergenic and non-allergenic components extracted from an allergen source (e.g., fish allergen extract) |
| Allergen source/carrier |
Origin/starting material of allergens (e.g., fish). |
| α-Gal |
Galactose-α-3-galactose, a disaccharide as a cause of anaphylaxis to mammalian meat, gelatin, and biologics |
| Ara h 2 |
2S albumin, a storage protein of peanut, associated with systemic reactions in peanut allergy |
| Api g 1 |
Celery allergen with homology to Bet v 1, responsible for birch pollen-associated cross-reactions |
| Bet v 1 |
Immunodominant major allergen in birch pollen (Betula verrucosa) |
| Bet v 2 |
Birch pollen profilin, minor allergen, which as a panallergen in numerous pollens and plant foods (e.g., melon) can be responsible for cross-reactions and thus complicates diagnosis |
| CCD |
Cross-reactive carbohydrate determinants. They represent epitopes of N-glycans, and less often of O-glycans, as panallergens, are responsible for a pronounced cross-reactivity. |
| Cor a 1.04 |
Hazelnut allergen with homology to Bet v 1, responsible for birch pollen-associated cross-reactions |
| Dau c 1 |
Carrot allergen with homology to Bet v 1, responsible for birch pollen-associated cross-reactions |
| Gad c 1 |
Major cod allergen (Ca2+ transport protein, parvalbumin, major fish allergen) |
| Gly m 4 |
Soy allergen with homology to Bet v 1, responsible for birch pollen-associated, sometimes severe cross-reactions |
| Cross-reactive |
Similarity-induced immunological reaction with molecular structures that were not responsible for the original sensitization |
| LTP |
Lipid transfer proteins; thermo- and digestion-stable allergens of plant origin |
| Mal d 1 |
Apple allergen with homology to Bet v 1, responsible for frequent birch pollen-associated, mostly oropharyngeal cross-reactions |
| MUXF3 |
Designation of the structure of a carbohydrate side chain of plant glycoproteins and allergens that can potentially be bound by IgE antibodies, corresponds to a specific type of CCD (see above) |
| Oleosins |
Lipophilic and thermostable allergens in nuts and oilseeds. |
| Pen a 1 |
Tropomyosin (muscle structure protein) of shrimp with homologous proteins in other arthropods and cause of cross-reactions |
| PR-10 |
„Pathogenesis-related protein family 10“; Bet-v-1 homologous proteins with defense function in plants (including tree pollen, food) |
| Pru p 3 |
Lipid transfer protein in peach responsible for systemic reactions in patients in the Mediterranean region |
| Recombinant |
Produced with the aid of genetically modified (micro)organisms |
| Recombinant allergen |
Allergenic protein often produced in Escherichia coli without the carbohydrate side chains found in native allergens |
| Sensitization |
Allergenicity (only relevant in case of corresponding symptoms) |
| Tri a 19 |
ῳ-5-gliadin in wheat, responsible for systemic reactions and effort-dependent anaphylaxis in wheat allergy |
