Table 5.
DEGs of psoriasis and cSCC significantly enriched in IL-17 signaling pathway.
| Sr. no. | Psoriasis DEGs | Average Expressions | cSCC DEGs | Average Expressions |
|---|---|---|---|---|
| 1 | CXCL2 | 7.143566 | SRSF1 | 11.30402 |
| 2 | S100A8 | 13.03884 | TNF | 3.775442 |
| 3 | S100A9 | 11.57422 | S100A8 | 10.50457 |
| 4 | LCN2 | 10.42698 | ELAVL1 | 7.146701 |
| 5 | CCL20 | 7.295939 | TRAF6 | 5.351013 |
| 6 | CXCL8 | 7.35222 | LCN2 | 5.506456 |
| 7 | FOSL1 | 6.836052 | MAPK11 | 4.413777 |
| 8 | IL1B | 7.299115 | CXCL3 | 4.455207 |
| 9 | CXCL1 | 7.507195 | DEFB4A | 7.363343 |
| 10 | S100A7 | 13.38452 | JUN | 9.363052 |
| 11 | MMP1 | 7.214311 | DEFB4B | 7.363343 |
| 12 | IFNG | 5.405429 | IKBKG | 6.876049 |
| 13 | CXCL10 | 8.052625 | TRAF3IP2 | 3.874313 |
| 14 | MAPK14 | 8.921881 | FOSL1 | 4.520605 |
| 15 | CCL2 | 9.811309 | MAPK3 | 7.049278 |
| 16 | MMP9 | 8.010812 | S100A9 | 8.624269 |
| 17 | IL17D | 9.42729 | IL1B | 3.671266 |
| 18 | MAPK13 | 11.11599 | CCL20 | 4.261092 |
| 19 | TAB3 | 5.693991 | MAPK10 | 4.192857 |
| 20 | IL17A | 3.848178 | MAPK9 | 4.239504 |
| 21 | CCL7 | 4.973044 | TRAF2 | 5.059843 |
| 22 | IL17F | 5.032107 | S100A7 | 10.17163 |
| 23 | IKBKE | 6.796894 | JUND | 3.783349 |
| 24 | IL17RE | 8.205539 | HSP90AA1 | 11.51992 |
| 25 | ANAPC5 | 7.907747 | MAPK14 | 5.104123 |
| 26 | FOS | 8.704977 | MMP3 | 4.519938 |
| 27 | MAP3K7 | 7.460711 | ||
| 28 | MMP13 | 4.249849 | ||
| 29 | TRADD | 8.777471 | ||
| 30 | MMP9 | 6.08175 | ||
| 31 | MMP1 | 5.822357 | ||
| 32 | CXCL8 | 3.900222 | ||
| 33 | CXCL1 | 4.924705 | ||
| 34 | IKBKE | 6.151091 |
The average expression values were calculated for microarray datasets. The DEGs of psoriasis are of lesional vs non-lesional and lesional vs normal groups. The DEGs of cSCC are of cSC-insitu vs normal and cSCC-invasive vs normal groups