Fig. 3. Human STAT5A and STAT5B share 92% identity.
STAT5A and STAT5B display approximately 92% identity (731 amino acids out of 794). However, they additionally share 12 similar amino acid positions, which makes them approximately 94% similar. STAT5A consists of 794 amino acids and STAT5B of 787 amino acids, with STAT5B lacking 12 C-terminal amino acids present in STAT5A. Based on the first 774 and 779 amino acids of STAT5A and STAT5B, respectively, both proteins are ~94% identical and ~95% similar. Phosphorylation sites are highlighted by red arrows and the data were collected from PhosphoSitePlus® (see also Fig. 2).