Figure 5. DNA copy number alterations.
DNA copy number alterations of 17 tumors from 15 patients subjected to targeted massively parallel sequencing showed homozygous deletions at the loci encoding RB1 (18%), BRCA2 (12%), TP53 (12%), TSC2 (6%) and CDKN2A (6%) were the most common. Amplifications were present in FGFR3, NTRK1 and ERBB3 (each 6%). Chromosomes are shown along the x-axis, and cases along the y-axis. Homozygous deletions, dark blue; losses, light blue; gains, orange; amplifications, red.