Figure 3.
Proteomic analysis revealed LRT-EVs to contain proteins derived from numerous cellular compartments and of variable functional class. 25(OH)VD, 25-hydroxyvitamin D; Ang II, angiotensin II; Ang III, angiotensin III, ANP, atrial natriuretic peptide; Ca2+, calcium ion; Cl−, chloride ion; CLIC, chloride intracellular channel protein; Cyst, cystine, FABP, fatty acid-binding protein; GPRC5C, G-protein coupled receptor family C group 5 member C; H+, hydrogen ion; H2O2, hydrogen peroxide; K+, potassium ion; Na+, sodium ion; O2, oxygen; Pi, inorganic phosphate; ROS, reactive oxygen species; SGLT, sodium-glucose cotransporter; SLC; solute carrier family member; SOD, superoxide dismutase, VDAC, voltage-dependent anion channel.