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. 2020 Aug 25;1(2):zqaa013. doi: 10.1093/function/zqaa013

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© The Author(s) 2020. Published by Oxford University Press on behalf of American Physiological Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Decreased Fat Oxidation and Energy Expenditure Do Not Contribute to the Development of Obesity. (A–D) Total activity, fat oxidation, CHO oxidation, and energy expenditure in lean and obese mice when averaged over the middle of the second light cycle (ie, 10–13 h) during 48 h of indirect calorimetry. (E–H) Total activity, fat oxidation, CHO oxidation, and energy expenditure in lean and obese mice when averaged over the middle of the second dark cycle (ie, 22–1 h) during 48 h of indirect calorimetry. Data expressed as mean ± SEM of results obtained from n = 4–10 for each genotype. *P < .05 versus lean (unpaired two-tailed Student’s t-test).