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. Author manuscript; available in PMC: 2021 Jul 13.
Published in final edited form as: Matrix Biol. 2020 Oct 9;95:15–31. doi: 10.1016/j.matbio.2020.10.002

Figure 2.

Figure 2.

Three-dimensional reconstruction of wild type mouse zonule at 1 month of age, visualized by fibrillin-1 immunofluorescence. A. Maximum intensity orthographic projection of the zonule showing the anterior (ant.), equatorial (eq.), and posterior (post.) fibers as they approach the lens. The posterior fibers connect to the fibrillar girdle (FG) at the lens surface. B. XZ projections show the zonule from the lateral aspect (for orientation, see Fig. 1B). C. An individual optical section from 100 μm above the equatorial lens surface (position arrowed in B). D. An optical section from immediately above the lens surface (z = 0 μm, arrowed in B). Note the presence of channels (*1-3) in the zonular fibers. The channels meander but are generally oriented to the anterior-posterior axis. E. YZ projections show the channels in transverse section. They are approximately 30 μm wide and 50 μm high. F. Volumetric projection of individual zonular fibers showing their branched organization. Scale bars = 50 μm.