Table 1.

Patient presentation, clinical course and outcome

Patient	1	2	3
Gender	Female	Male	Male
Age	57	50	45
Nationality	Filipino	Filipino	Filipino
Medical history	DM untreated, HbA1c: 15%	DM untreated, alcoholism	DM, illicit drug use, Klebsiella pneumoniae deep neck abscess successfully treated 9 months previously
Signs and symptoms	Fever, confusion, stiff neck, left hemiparesis	Fever, confusion, stiff neck, seizures	Fever, confusion, stiff neck
Blood glucose	840 mg/dl	443 mg/dl	794 mg/dl
CSF analysis	WBC: 800 (90% PMN), Glu: 391 mg/dl, Prot.: 95 mg/dl	WBC: 40,000 (98% PMN) Glu: 114 mg/dl, Prot.: 1,017	WBC: 290,000 (90% PMN), Glu 116 mg/dl, Prot.: 14,640 mg/dl
CSF culture	Klebsiella pneumoniae	K. pneumoniae	K. pneumoniae/ozaenae
Blood culture	K. pneumoniae	K. pneumoniae	Negative
Abdominal U/S	Not done	Not done	Negative for liver abscess
CT scan	Brain unremarkable (on admission and follow-up), abscesses in liver segment VII and spleen	Brain on admission unremarkable, at 48 h follow-up SAH/severe brain oedema. Abscesses in both lungs and liver segment VII	A few hypodense lesions of the brain stem and white matter
Antibiotic treatment on admission	Ceftriaxone, vancomycin, ampicillin/sulbactam + dexamethasone	Ceftriaxone, vancomycin, +dexamethasone	Meropenem, vancomycin, colistin+ dexamethasone
ICU LOS	21 days	4 days	14 days
Final outcome	Death in ICU due to MOF	Death in ICU due to cerebral oedema	Death in ICU due to MOF

DM, diabetes mellitus; CSF, cerebrospinal fluid; LOS, length of stay; MOF, multiple organ failure; SAH, subarachnoid haemorrhage.