Suri 2016.
| Study characteristics | ||
| Methods |
Study type: RCT (split‐mouth design) Duration of trial: not mentioned in the study Duration of follow‐up: 2 months |
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| Participants |
Setting: Department of Periodontics, Patil Dental College and Hospital, India Inclusion criteria: patients in good systemic health, good oral hygiene, and clinically demonstrable dentine hypersensitivity teeth, specifically canines and premolars, which were reliable in their response to test measurements Exclusion criteria: patients with any systemic or psychological diseases, constant use of analgesic, antiinflammatory drugs, or allergic responses to dental products, carious lesions, defective restorations, fractures, prosthesis or orthodontics appliances, periodontal pockets, mobility, or evidence of pulpits and those who have used any desensitizing agents or undergone any periodontal surgery in the last 6 months Total number: 30 participants (120 teeth) Age range: 40 to 49 years Sex (M/F): 15/15 |
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| Interventions |
Group 1: placebo‐controlled group, distilled water was applied by means of a cotton swab for 20 s Group 2: after isolation, 50% NaF varnish was painted on the sensitive surface with a disposable microbrush as per the manufacturer's instructions for 60 s. The cotton roll was removed to allow saliva or moisture to set the varnish Group 3: 980 nm diode laser was applied at 2 W power in a continuous wave mode on the test tooth surface, no contact mode using a fiber of 320 micron diameter held perpendicular to the irradiated surface at a distance of 1 mm. Each area was irradiated twice for 20 s Group 4: treated with both 5% NaF varnish and 980 nm diode laser described in group 2 and 3. NaF varnish was left on the tooth surface for 60 s before the irradiation |
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| Outcomes | Response to tactile and air blast stimuli was recorded as VAS score at baseline, 24 hours, 1 week, 1 month, and 2 months | |
| Notes |
Baseline characteristics: 1. scaling and polishing was done for all the patients 1 week before the study and subjects were instructed not to use any other desensitizing agents during the study. All patients were taught modified Stillman technique and were instructed to use the same with non‐desensitizing toothpastes and soft bristle tooth brushes; 2. degree of severity was measured in response to tactile stimuli with explorer applied in light pressure on facial surface in mesio‐distal movement on cervical area; 3. air blast stimuli was performed with air syringe (air pressure 25–28 psi) of the dental unit at normal room temperature for 1 s at a distance of 1 cm from the tooth surface; 4. dentine hypersensitivity was assessed by patient's indication of the severity of pain related to each tooth immediately after each stimulus, according to VAS; 5. the sensitivity patterns were recorded at baseline, 24 hours, 1 week, 1 month, and 2 months Sample size calculation: not mentioned in the study Source of funding: none Ethics approval: not mentioned in the study Informed consent: quote: "Participants were informed about the purpose of the investigation and signed an appropriate informed consent form" Adverse events: none. Quote: "Complications such as detrimental pulpal effects or allergic reactions were not observed during this period. All teeth remained vital after treatment, with no reported adverse reactions or clinically detectable complications" |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Low risk | Quote: "Randomization sequence was generated using a table of random numbers" Comment: probably done |
| Allocation concealment (selection bias) | Unclear risk | Insufficient information provided |
| Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | The study consists of 4 groups, 1 of which is placebo. Inclusion of a placebo group in the experiment may indicate an attempt to blind participants, however it is considered insufficient as the patients may be aware of the nature of the treatment groups |
| Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Insufficient information provided |
| Incomplete outcome data (attrition bias) All outcomes | Low risk | Quote:"A total of 120 teeth in thirty patients completed the 2month study period" |
| Selective reporting (reporting bias) | Low risk | All intended outcomes were reported |
| Other bias | Low risk | No other sources of bias were identified Sample size calculation and ethics approval were not reported |