TABLE 1.
Nominal and Mean Calculated Concentrations With Accuracy and Precision of HCQ in Plasma and Blood
| Analyte | Nominal Concentration (mcg/mL) | Intraday (n = 6) | Interday (n = 6) | ||||
| Measured Mean Concentration (mcg/mL) | Accuracy (%) | Precision (%) | Measured Mean Concentration (mcg/mL) | Accuracy (%) | Precision (%) | ||
| HCQ plasma | 0.0150 | 0.0157 | 104 | 5.3 | 0.0169 | 112 | 8.0 |
| 0.0600 | 0.0682 | 114 | 0.5 | 0.0554 | 92.3 | 1.4 | |
| 0.600 | 0.551 | 91.8 | 1.8 | 0.575 | 95.7 | 9.9 | |
| 1.125 | 1.19 | 105 | 7.5 | 1.20 | 107 | 7.6 | |
| HCQ blood | 0.050 | 0.0456 | 91.1 | 4.1 | 0.0513 | 103 | 6.7 |
| 0.150 | 0.157 | 104 | 3.9 | 0.151 | 100 | 1.4 | |
| 1.50 | 1.47 | 98.1 | 0.8 | 1.43 | 95.3 | 3.8 | |
| 4.00 | 4.02 | 100 | 3.1 | 4.11 | 103 | 2.5 | |