Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The function of the tripartite pump MacAB-TolC in toxin secretion and macrolide resistance. MacAB secretes ribosomally synthesized and post-translationally modified peptides (RiPPs), such as enterotoxin STII, that are targeted and exported to the periplasm by the SecY-secretion signal (purple). Following cleavage and disulfide bond formation in the periplasm, the toxin is then secreted out by the MacAB-TolC. Figure modified based on Crow et al.431
