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. 2021 Jun 29;12:690121. doi: 10.3389/fpsyt.2021.690121

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Copyright © 2021 Lang, Wen, Li, Yin, Wang and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Time course of the average hemoglobin concentration of 10 people under verbal fluency task (VFT) (A). Time course of the average hemoglobin concentration of 10 anxiety and depression patients at the acute (B), consolidation (C), and maintenance stages (D). All of them completed the VFT. The red line indicates the amount of change in oxyhemoglobin concentration (oxy-Hb), and the black line indicates the amount of change in deoxyhemoglobin concentration (deoxy-Hb). The numbers indicate integral values.