Table 3. Cu-Catalyzed Hydrocarboxylation of Alkanesa.
| yield,
%b |
||
|---|---|---|
| alkane | products | totalc |
| cyclohexane | 30.0 (cyclohexanecarboxylic acid, C6H11COOH) | 31.5 |
| 1.2 (cyclohexanone, C6H10O) | ||
| 0.3 (cyclohexanol, C6H11OH) | ||
| propane | 22.0 (isobutyric acid, (CH3)2CHCOOH) | 28.2 |
| 6.2 (n-butyric acid, C3H8COOH) | ||
a
Reaction conditions: cyclohexane (1 mmol) or propane (1 atm), CO (20 atm), 2 (2.5 μmol), CH3CN (4 mL), H2O (2 mL), K2S2O8 (1.5 mmol), 3 h, 60 °C, stainless-steel autoclave (20 mL capacity).
b
Yields are based on alkane: (moles of product)/(mole of cycloalkane) × 100%.
c
Sum of the yields of all products.