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. 2021 May 19;106(8):2198–2207. doi: 10.1210/clinem/dgab304

Table 5.

Prevalence of RAS variants among 50 644 thyroid FNA samples by Bethesda category

RAS gene AUS/FLUS (III) FN/SFN (IV) SFM (V) Malignant (VI)
HRAS variant 1156 (2.93%) 495 (5.22%) 12 (1.43%) 4 (0.47%)
KRAS variant 314 (0.80%) 129 (1.36%) 12 (1.43%) 6 (0.70%)
NRAS variant 1712 (4.34%) 681 (7.18%) 29 (3.46%) 7 (0.82%)
Any RAS variant 3179 (8.06%) 1304 (13.74%) 53 (6.33%) 17 (1.99%)

Some samples contained more than 1 RAS variant. Table 1 reports the total number of samples in each Bethesda category and the Bethesda category abbreviations.

Abbreviation: FNA, fine-needle aspiration.