. 2021 Jun 24;5(6):e25043. doi: 10.2196/25043

Table 4.

Metabolic health parameters assessed at t=0, 8, and 16 weeks.

Parameter	t=0 weeks, mean (SD)	t=8 weeks, mean (SD)	t=16 weeks, mean (SD)	P value
Glucose (mmol/L)	5.61 (0.67)^a	5.63 (0.64)^a	5.84 (0.63)^a	.04
C-peptide (nmol/L)	0.52 (0.32)^a	0.52 (0.23)^a	0.43 (0.16)^a	.01
HOMA-IR^b	7.45 (5.27)^a	7.42 (3.95)^a	6.31 (2.57)^a	.049
Triglycerides (mmol/L)	1.67 (0.86)^a	1.43 (0.60)^a	1.39 (0.55)^a	.02
Total cholesterol (mmol/L)	6.23 (0.78)	5.91 (0.84)^a	5.90 (0.86)^a	0.01
HDL^c cholesterol (mmol/L)	1.14 (0.28)^a	1.09 (0.28)^a	1.44 (0.36)^a	<.001
LDL^d cholesterol (mmol/L)	4.34 (0.74)^a	4.18 (0.79)^a	3.87 (0.78)^a	<.001
Systolic blood pressure (mm Hg)	135 (18.2)	133 (13.7)	132 (17.1)	.70
Diastolic blood pressure (mm Hg)	78.6 (9.60)	80.3 (8.93)	79.6 (9.77)	.30
BMI (kg/m²)	29.9 (3.94)^a	29.4 (3.60)^a	29.2 (3.66)^a	<.001
Waist circumference (cm)	102 (11.5)^a	100 (9.43)^a	99.4 (8.86)^a	.01
Health score (arbitrary units)	1.30 (0.31)	1.23 (0.30)	1.57 (0.32)	<.001

^aNo significant difference following the post hoc analysis.

^bHOMA-IR: homeostatic model assessment–insulin resistance; calculated based on glucose and C-peptide [50].

^cHDL: high-density lipoprotein.

^dLDL: low-density lipoprotein.