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. 2021 Jun 24;9(6):e28277. doi: 10.2196/28277

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©Meng Wang, Haofen Wang, Xing Liu, Xinyu Ma, Beilun Wang. Originally published in JMIR Medical Informatics (https://medinform.jmir.org), 24.06.2021.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Medical Informatics, is properly cited. The complete bibliographic information, a link to the original publication on https://medinform.jmir.org/, as well as this copyright and license information must be included.

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A drug knowledge graph is shown on the left with missing relations represented as dotted lines. There is usually no direct DDI relation between drugs. DDI descriptions from the biomedical text are shown on the right. The words in red represent concerns regarding DDI information in terms of both adverse DDIs and in-depth ways drugs can interact in pharmacology. DDI: drug-drug interaction.