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. 2021 Jun 29;9:671821. doi: 10.3389/fcell.2021.671821

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Copyright © 2021 Pan, Huang and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The m5C status was different between the high- and low-risk groups and the expression of m5C-related lncRNAs differed in vitro. (A) Principal component analysis (PCA) was performed for the low- and high-risk groups based on the whole genome and m5C-related coding genes, and a risk model was constructed using 14 m5C-related lncRNAs. (B) Gene set enrichment analysis of m5C-related lncRNAs. (C) Expression level of m5C-related lncRNAs in BEAS-2B cells and LUAD cells. *p < 0.5, **p < 0.01, ***p < 0.001, and **** p < 0.0001. ns, no sense.