Skip to main content
. 2021 Jun 29;11:650316. doi: 10.3389/fonc.2021.650316

Figure 4.

Figure 4

SVZ SOX2+ progenitor number is altered by LV-proximal GBM. (A–C) Representative images of SOX2+ cells in the GFP-/HuNu- cells of the SVZ in (A) LV-proximal, (B) LV-intermediate, and (C) LV-distal groups. Scale bar = 100 μm. (D) Quantification of SOX2+ cell density in the SVZ of LV-proximal, LV-intermediate, and LV-distal GBM mice. (E–G) Representative images of GFAP+/SOX2+ cells in the SVZ of (E) LV-proximal, (F) LV-intermediate, and (G) LV-distal groups. Scale bar = 100 μm. (H) Quantification of GFAP+/SOX2+ cell density in the SVZ of LV-proximal (n = 7), LV-intermediate (n = 5), and LV-distal (n = 5) GBM mice. Data are presented as mean ± SEM. **p < 0.01, ****p < 0.0001.