Table 4.
Psychological Responses to Testing in the Post-Testing Survey. P-values Calculated by Comparing Responses of Each Question (Grouped as Never/Rarely, and Sometimes/Often) Between Study Arms
| PGx-Only Arm (n=21) | PGx Plus MTM Study (n=17) | ||||
|---|---|---|---|---|---|
| Never/Rarely | Sometimes/Often | Never/Rarely | Sometimes/Often | P-value | |
| Felt upset about my test result | 20 | 1 | 16 | 1 | 1 |
| Felt sad about my test result | 20 | 1 | 16 | 1 | 1 |
| Felt anxious or nervous about my test result | 19 | 2 | 15 | 2 | 1 |
| Felt guilty about my test result | 21 | 0 | 17 | 0 | NA |
| Felt relieved about my test result | 9 | 12 | 5 | 12 | 0.51 |
| Felt happy about my test result | 7 | 14 | 3 | 14 | 0.46 |
| Felt a loss of control | 20 | 1 | 16 | 1 | 1 |
| Had problems enjoying life because of my test results | 21 | 0 | 16 | 1 | 0.45 |
| Worried about my risk of having a side effect or my medication not working | 17 | 4 | 13 | 4 | 1 |
| Uncertain about what my test result means about how I will respond to medications | 17 | 4 | 12 | 5 | 0.70 |
| Uncertain about what my test result means for my child(ren) and/or family’s response to medications | 21 | 0 | 14 | 3 | 0.08 |
| Had difficulty making decisions about my medications | 19 | 2 | 16 | 1 | 1 |
| Understood clearly my choices for prevention or early detection of side effects | 10 | 11 | 1 | 16 | 0.01 |
| Felt frustrated that there are no definite guidelines to prevent side effects or medications that do not work for me based on the test results | 17 | 4 | 12 | 5 | 0.70 |
| Thought about how my test results affected my work or family life | 21 | 0 | 14 | 3 | 0.08 |
| Felt concerned about how my test results will affect my health insurance coverage | 19 | 2 | 15 | 2 | 1 |
| Had difficulty talking about my test results with family members | 20 | 1 | 16 | 1 | 1 |
| Felt that my family was supportive during the testing process | 9 | 12 | 1 | 16 | 0.01 |
| Felt satisfied with my family communication about my test result | 8 | 13 | 1 | 16 | 0.03 |
| Worried that the testing process has brought about conflict within my family | 21 | 0 | 17 | 0 | NA |
| Felt regret about getting my test results | 21 | 0 | 17 | 0 | NA |
| Worried about the possibility of my children having side effects or being prescribed a drug not likely to work for them* | 12 | 5 | 9 | 3 | 1 |
| Felt guilty about possibly passing on a pharmacogenetic risk to my children* | 15 | 2 | 10 | 2 | 1 |
Note: *These questions were only asked of participants who indicated that they had children.