Table 1.
The IC50 (μM) of pyrazolyl derivatives against different tumor cell lines.
| Compound | R | IC50 (μM) | ||
|---|---|---|---|---|
| MCF-7 | HepG2 | HCT-116 | ||
| 1 | Br | 17.8 ± 0.5 | 4.4 ± 0.4 | 4.2 ± 0.2 |
| 2 | NO2 | 94.2 ± 0.3 | 34.6 ± 2.6 | 17.3 ± 0.5 |
| Doxorubicin | — | 4.7 ± 0.08 | 3.9 ± 0.06 | 4.4 ± 0.04 |
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