Table 2.
Xanthine oxidase inhibition activities of pyrazole derivatives (1 and 2).
| Compound | Binding free energy (kcal/mol) | IC50 (μM) |
|---|---|---|
| 1 | −7.6 | 0.83 ± 1.36 |
| 2 | −6.1 | 14.50 ± 2.25 |
| Allopurinol | — | 14.97 ± 1.61 |
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