Table 4.
Correlation of BDNF with anthropometric, cognitive, glycemic, and lipid profile parameters in non-obese and obese populations
| Variable | Non-obese group (n= 66) | Obese group (n= 66) | ||
|---|---|---|---|---|
| r | P | r | P | |
| BMI (kg/m2) | –0.596 | < 0.001 | –0.658 | < 0.001 |
| WHR | –0.166 | 0.183 | –0.267 | 0.030 |
| ERPs-P300 latency (ms) | –0.454 | < 0.001 | –0.674 | < 0.001 |
| ERPs-P300 amplitude (mV) | 0.028 | 0.822 | 0.507 | < 0.001 |
| ART (ms) | –0.232 | 0.061 | –0.283 | 0.021 |
| VRT (ms) | –0.232 | 0.061 | –0.524 | < 0.001 |
| STMT time (sec) | –0.162 | 0.192 | –0.137 | 0.272 |
| No. of errors | 0.148 | 0.234 | 0.141 | 0.259 |
| SCT time (sec) | –0.080 | 0.528 | –0.292 | 0.017 |
| No. of errors | –0.207 | 0.096 | –0.545 | < 0.001 |
| Mini CAQ score | 0.070 | 0.573 | 0.725 | < 0.001 |
| MMSE score | 0.004 | 0.977 | 0.530 | < 0.001 |
| FDST | 0.003 | 0.981 | 0.272 | 0.027 |
| RDST | 0.236 | 0.056 | 0.534 | < 0.001 |
| FBG (mg/dL) | –0.023 | 0.855 | –0.794 | < 0.001 |
| HbA1c | –0.221 | 0.145 | –0.577 | < 0.001 |
| Insulin (µIU/mL) | –0.029 | 0.849 | –0.660 | < 0.001 |
| HOMA-IR | –0.010 | 0.935 | –0.785 | < 0.001 |
| TC (mg/dL) | –0.018 | 0.888 | –0.619 | < 0.001 |
| TG (mg/dL) | –0.212 | 0.087 | –0.701 | < 0.001 |
| HDL-C (mg/dL) | 0.232 | 0.060 | 0.573 | < 0.001 |
| LDL-C (mg/dL) | –0.178 | 0.154 | –0.673 | < 0.001 |
| Atherogenic index | –0.204 | 0.101 | –0.682 | < 0.001 |
Pearson correlation was used. A P-value < 0.05 considered statistically significant. BDNF, brain-derived neurotrophic factor; BMI, body mass index; WHR, waist to hip ratio; ERPs-P300, event-related potentials P300; ART, auditory reaction time; VRT, visual reaction time; STMT, symbol trail making test; SCT, symbol cancellation test; Mini-CAQ, mini-cognitive assessment questionnaire; MMSE, mini-mental state examination; FDST, forward digit span test; RDST, reverse digit span test; FBG, fasting blood glucose; HbA1c, glycated hemoglobin; HOMA-IR, homeostatic model assessment of insulin resistance; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.