Table 6.

Multiple linear regression analysis of BDNF (independent variable) with cognitive parameters (as dependable variables) in non-obese and obese groups

Independent variable	Non-obese group (n= 66)				Obese group (n= 66)
	Standardized coefficient β	95% CI of unstandardized β		P	Standardized coefficient β	95% CI of unstandardized β		P
		LB	UB			LB	UB
MMSE	0.010	–0.015	0.017	0.939	0.500	0.050	0.126	< 0.001
ERPs-P300
Latency (ms)	–0.455	–0.609	–0.209	< 0.001	–0.152	–0.299	0.071	0.222
Amplitude (mV)	0.030	–0.144	0.183	0.814	0.565	0.088	0.188	< 0.001
ART (ms)	–0.231	–0.001	0.000	0.063	–0.357	–0.001	0.000	0.003
VRT (ms)	–0.231	–0.001	0.000	0.063	–0.563	–0.002	–0.001	< 0.001
Mini-CAQ	0.073	–0.029	0.055	0.549	0.706	0.113	0.188	< 0.001
FDST	0.004	–0.028	0.029	0.973	0.332	0.006	0.036	0.006
RDST	0.236	–0.001	0.067	0.056	0.461	0.020	0.057	< 0.001
SCT (sec)	–0.084	–0.409	0.204	0.505	–0.271	–0.460	–0.028	0.028
SCT, no. of errors	–0.208	–0.018	0.001	0.094	–0.576	–0.067	–0.032	< 0.001

A P-value < 0.05 considered statistically significant.

BDNF, brain-derived neurotrophic factor; CI, confidence interval; LB, lower bound; UB, upper bound; MMSE, mini-mental state examination; ERPs-P300, event-related potentials P300; ART, auditory reaction time; VRT, visual reaction time; Mini-CAQ, mini-cognitive assessment questionnaire; FDST, forward digit span test; RDST, reverse digit span test; SCT, symbol cancellation test.