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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: J Allergy Clin Immunol Pract. 2021 Jan 19;9(7):2867–2873.e1. doi: 10.1016/j.jaip.2020.12.026

Table 1.

Demographic and clinical characteristics of African-American and White children with food allergy enrolled in FORWARD

Total Northwestern/Lurie Rush CCHMC CNHS
n (%) n (%) Odds Ratio (95% CI)7 n (%) Odds Ratio (95% CI) n (%) Odds Ratio (95% CI) n (%) Odds Ratio (95% CI)
Individual Demographics
Total n=664 664 (100) 226 (100) 133 (100) 158 (100) 147 (100)
Race
African-American 239 (36.0) 70 (31.0) 1 (ref) 75 (56.4) 44 (27.9) 50 (34.0)
White 425 (64.0) 156 (69.0) 58 (43.6) 0.35 (0.22 – 0.54) *** 114 (72.2) 1.16 (0.74 – 1.82) 97 (66.0) 0.87 (0.56 – 1.35)
Gender1
Male 411 (62.7) 130 (57.8) 89 (68.5) 96 (61.9) 96 (63.8)
Female 245 (37.4) 95 (42.2) 1 (ref) 41 (31.5) 0.63 (0.40–0.99)* 59 (38.1) 0.84 (0.55 – 1.27) 50 (32.9) 0.71 (0.46 – 1.09)
Current Age in Years2
< 5 229 (35.0) 62 (27.7) 39 (30.0) 59 (38.3) 69 (47.3)
>=5 425 (65.0) 162 (72.3) 1 (ref) 91 (70.0) 0.89 (0.55 – 1.44) 95 (61.7) 0.62 (0.40 – 0.95)* 77 (52.7) 0.43 (0.28 – 0.67)***
Household Demographics
Total n=619 619 (100) 208 (100) 124 (100) 153 (100) 134 (100)
Income3
< $50K 123 (22.9) 39 (21.4) 36 (34.3) 30 (22.9) 18 (15.0)
$50k-$99k 94 (17.5) 22 (12.1) 20 (19.1) 36 (27.4) 16 (13.3)
100k+ 321 (59.7) 121 (66.5) 1 (ref) 49 (46.7) 0.44 (0.27 – 0.72) ** 65 (49.6) 0.50 (0.31 – 0.79)** 86 (71.7) 1.27 (0.77 – 2.10)
Comorbidities
Total 664 (100) 226 (100) 133 (100) 158 (100) 147 (100)
Asthma4
Yes 247 (38.9) 88 (39.5) 1 (ref) 52 (42.3) 1.09 (0.70 – 1.72) 57 (38.8) 0.94 (0.61 – 1.44) 50 (35.2) 0.81 (0.52 – 1.26)
No 369 (58.1) 126 (56.5) 68 (55.3) 87 (59.2) 88 (62.0)
Outgrown 19 (3.0) 9 (4.0) 3 (2.4) 3 (2.0) 4 (2.8)
Allergic Rhinitis5
Yes 297 (46.9) 98 (44.0) 1 (ref) 65 (47.5) 1.41 (0.91 – 2.19) 67 (45.6) 1.06 (0.70 – 1.62) 68 (47.9) 1.17 (0.76 – 1.79)
No 337 (53.2) 125 (56.1) 59 (43.1) 80 (54.4) 74 (52.1)
Eczema6
Yes 524 (81.9) 185 (83.0) 1 (ref) 90 (73.8) 0.58 (0.34 – 0.98)* 126 (85.1) 1.17 (0.66 – 2.08) 119 (83.8) 1.06 (0.60 – 1.87)
No 115 (18.1) 38 (17.0) 32 (26.2) 22 (14.9) 23 (16.2)
1

n=8 individuals (1.2%) had missing gender data; n=1 from NU/Lurie, n=3 from Rush, n=3 from CCHMC, n=1 from CNHS

2

n=10 individuals (1.5%) had missing age data; n=2 from NU/Lurie, n=3 from Rush, n=4 from CCHMC, n=1 from CNHS

3

n=81 households (13.1%) had missing income data or declined to answer; n=26 from NU/Lurie, n=19 from Rush, n=22 from CNHS, n=14 from CCHMC

4

n=29 individuals (4.4%) had missing asthma data; n=3 from NU/Lurie, n=10 from Rush, n=11 from CCHMC, n=5 from CNHS

5

n=30 individuals (4.5%) had missing data on allergic rhinitis; n=3 from NU/Lurie, n=11 from Rush, n=11 from CCHMC, n=5 from CNHS

6

n=29 individuals (4.4%) had missing data on eczema; n=3 from NU/Lurie, n=11 from Rush, n=10 from CCHMC, n=5 from CNHS

7

Odds ratios represent the unadjusted probability estimate of the italicized row in each recruitment center compared to NU/Lurie (reference group). Odds ratios for income are based on probability of earning > 100k versus <$50k and for asthma are based on having asthma (outgrown asthma, n=19 was excluded) versus not having asthma.

Bold values represent statistical significance;

*

P < 0.05;

**

P < 0.01;

***

P < 0.001