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. Author manuscript; available in PMC: 2021 Jul 14.
Published in final edited form as: Photochem Photobiol. 2021 Feb 8;97(4):816–825. doi: 10.1111/php.13389

Figure 5.

Figure 5.

Granadaene photobleaching exerts little impact on beta-lactam antibiotic activity on GBS. (a) CFU Time kill assay of GBS exposed to 430 nm pulsed light and treated with 0.2 μg/mL of ampicillin. No significant changes in ampicillin performance observed. (b) CFU Time kill assay of ΔCylE GBS exposed to 430 nm pulsed light and treated with 0.2 μg/mL of ampicillin. No significant changes in ampicillin performance observed. (c) CFU Time kill assay of GBS exposed to 430 nm pulsed light and treated with 0.2 μg/mL of penicillin V. Only minor enhancement of penicillin V activity observed after 6 hours of incubation. (d) CFU Time kill assay of ΔCylE GBS exposed to 430 nm pulsed light and treated with 0.2 μg/mL of penicillin V. Only minor enhancement of penicillin V activity observed after 6 hours of incubation, although not as large as the enhancement observed in the pigment expressing GBS. ****: p < 0.0001; **: p < 0.01.