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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Cancer Res. 2021 Mar 26;81(13):3727–3737. doi: 10.1158/0008-5472.CAN-20-3290

Figure 1. Distribution of cisplatin in adult mouse brain.

Figure 1.

A, Schematic diagram of experimental design for cisplatin or vehicle administration. B, Representative platinum (Pt) distribution images of hippocampus sub-regions (dentate gyrus, CA1 and CA3) and prefrontal cortex from vehicle and cisplatin-treated mice using Imaging Mass Cytometry (IMC). Adult female mice were intraperitoneally injected with vehicle or cisplatin, and sacrificed at 2 and 5 weeks after the final vehicle or cisplatin injection. All scale bars: 100 μm for dentate gyrus, CA1, CA3, and prefrontal cortex.