A, Schematic diagram of experimental design for cisplatin or vehicle administration. B, Representative platinum (Pt) distribution images of hippocampus sub-regions (dentate gyrus, CA1 and CA3) and prefrontal cortex from vehicle and cisplatin-treated mice using Imaging Mass Cytometry (IMC). Adult female mice were intraperitoneally injected with vehicle or cisplatin, and sacrificed at 2 and 5 weeks after the final vehicle or cisplatin injection. All scale bars: 100 μm for dentate gyrus, CA1, CA3, and prefrontal cortex.