Figure 1.
Study sample selection for participants in the MESA analyses without heart failure at the time Ang1 and Ang2 were measured. Sample includes the MESA Cohort (baseline cross-sectional analyses) and the MESA Case-Cohort (longitudinal analyses). Cases were defined as all MESA participants with interpretable cMRI who developed incident heart failure or cardiovascular death through the follow up period. The MESA-Angiogenesis Cohort consisted of a randomly selected subset of MESA participants with available cMRI.