Table.

Etiopathogenic subclassifications of diabetes mellitus secondary to exocrine pancreatic disease, collectively referred to as pancreatogenic diabetes mellitus, grouped according to their proposed mechanisms. Adapted from Hart et al(2).

Congenital or acquired complete absence of islets:

Pancreatectomy (total)

Pancreatic agenesis

Acquired partial absence or dysfunction of islets:

Acute pancreatitis

Chronic pancreatitis*

Cystic fibrosis

Hemochromatosis

Pancreatectomy (partial)

Paraneoplastic:

Pancreatic ductal adenocarcinoma

^*Includes tropical pancreatitis, which was previously referred to as fibrocalculous pancreatopathy.