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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Neurotoxicol Teratol. 2021 Jun 8;86:107000. doi: 10.1016/j.ntt.2021.107000

Table 4.

Predicting infant outcomes from prenatal opioid and non-opioid substance exposure and covariates.

Prematurity
3M ASQ Fine Motor
6M ASQ Communication
b OR p b p R2 b p R2

1. Total opioid exposure 0.83 2.30 0.06 −0.32 0.01 0.12 −0.32 0.02 0.21
 Cigarettes/week 0.14 1.14 0.68 0.10 0.50 0.19 0.17
 Standard drinks/week 0.07 1.07 0.81 −0.14 0.17 −0.16 0.07
 Polysubstance risk 0.30 1.34 0.28 0.07 0.52 0.07 0.49
 Adjusted age (days) - - - 0.19 0.12 0.10 0.29
 Income - - - - - 0.27 0.01
1. MAT (% pregnancy) - - - −0.23 0.07 0.15 −0.25 0.02 0.24
 Illicit opioid use (% pregnancy) - - - −0.34 0.03 −0.24 0.11
 Cigarettes/week - - - 0.12 0.43 0.24 0.06
 Standard drinks/week - - - −0.15 0.09 −0.15 0.21
 Polysubstance risk - - - 0.13 0.16 0.12 0.31
 Adjusted age (days) - - - 0.20 0.08 0.12 0.20
 Adjusted age (days) - - - - - - 0.30 0.004

Note. Non-dichotomous variables were standardized prior to analyses. Significant findings in bold, marginal findings in italics. OR= Odds Ratio. ASQ = Ages and Stages Questionnaire-3rd Edition. MAT = medication-assisted treatment.