Table 2.

Selected microbiome biotech startups and ongoing projects

Microbiome	Company	Overview	Project	Stages
Plant	Pivot Bio	Nitrogen fixation	Corn supplement	Commercialized
	AgBiome	Pest control	Fungicide	Commercialized
	Boost Biomes	Manage disease of high-value crops	Reduce crop loss in the field and post-harvest	In development
Animal	Native Microbials	Restore highfunctioning lumen	Dairy	Commercialized
			Other animals	In development
	AnimalBiome	Personalized FMT	Pet dogs and cats	Commercialized
Human	Evelo Biosciences	Monoclonal microbials	COVID-19	Phase II/III
			Psoriasis	Phase II
			Triple-negative breast cancer	Preclinical
	Vedanta Biosciences	Defined consortia	Clostridium difficile infection	Phase II
			Inflammatory bowel disease	Phase I
			Cancer immunotherapy	Phase I
			Food allergy	Phase I
	Seres Therapeutics	Defined consortia	C. difficile infection	Phase III
			Ulcerative colitis	Phase II
			Metastatic melanoma	Phase I
	Synlogic Therapeutics	Smart living biotherapeutics	Phenylketonuria	Phase II
			Immune-oncology solid tumors	Phase I

Abbreviation: COVID-19, coronavirus disease 2019; FMT, fecal microbiota transplantation.