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. Author manuscript; available in PMC: 2022 Jul 19.
Published in final edited form as: Angew Chem Int Ed Engl. 2021 Jun 17;60(30):16382–16387. doi: 10.1002/anie.202104645

Table 3.

Substrate Scope of the Enantioselective β-C(sp3)−H Carbonylation of Cylcopropanecarboxylic Acids[a,b]

graphic file with name nihms-1704064-t0004.jpg
[a]

Conditions: 1 (0.1 mmol), Pd(OAc)2 (10 mol%), L13 (10 mol%), Mo(CO)6 (0.5 equiv), AgNO3 (2.0 equiv), HFIP (1.0 mL), 70 °C, 24 h.

[b]

Isolated yields of Bn-protected diacid 2’ are shown. The er values were determined on the SFC system using commercially available chiral columns.