Skip to main content
. Author manuscript; available in PMC: 2022 Jul 13.
Published in final edited form as: Lab Chip. 2021 Jul 13;21(14):2730–2737. doi: 10.1039/d1lc00293g

Figure 1.

Figure 1.

Scheme of the autonomous lab-on-paper platform for multiple, CRISPR-based diagnostics of SARS-CoV-2. A. Schematic illustration of the device configuration and working mechanism. The multiple RPA amplification reactor and CRISPR detection chambers were initially separated by a normally-closed, sucrose valve. B. Paper-based CRISPR chambers for multiplex gene diagnosis. The CRISPR-Cas12a detection reagents were pre-stored on the CRISPR detection chambers through lyophilization. C. Fluorescence image of multiple gene diagnostics of SARS-CoV-2 on the lab-on-paper platform. D. Photograph of the autonomous lab-on-paper platform.