Table 4:
Other outcome variables
| Variable | Manually adjusted GDT group (N=19) | Computer-assisted GDT group (N=19) | P value |
|---|---|---|---|
| Mean stroke volume index (ml.m−2) | 33.5 ± 7.5 | 40.9 ± 9.7 | 0.012 |
| Stroke volume index first 30 minutes (ml.m−2) | 34.8 ± 8.6 | 39.4 ± 9.6 | 0.129 |
| Stroke volume index last 30 minutes (ml.m−2) | 31.7 ± 8.4 | 42.1 ± 10.0 | 0.001 |
| Mean cardiac index (l.min−1.m−2) | 2.4 ± 0.4 | 3.2 ± 0.6 | <0.001 |
| Mean stroke volume variation (%) | 9.6 [7.6-12.5] | 7.3 [6.5-9.6] | 0.022 |
| Percentage of case time with | |||
| ➢ stroke volume index < 30 ml.m−2 | 22.6 [10.6-57.2] | 1.7 [0.0-31.5 ] | 0.030 |
| ➢ cardiac index < 2 l.min−1.m−2 | 21.6 [1.4-38.0] | 1.5 [0.0-3.7] | 0.001 |
| ➢ stroke volume variation < 13 % | 76.6 [60.8-88.3] | 96.1 [86.6-99.2] | 0.001 |
| ➢ MAP ± 10 mmHg of MAP target | 58.8 [48.3-70.5] | 97.2 [95.0-97.7] | <0.001 |
| ➢ MAP > 10 mmHg of MAP target | 12.9 [5.7-22.8] | 2.5 [1.5-4.9] | 0.001 |
| ➢ MAP < 65 mmHg | 1.9 [1.2-5.0] | 0.0 [0.0-0.0] | <0.001 |
| ➢ MAP < 60 mmHg | 0.4 [0.0-2.1] | 0.0 [0.0-0.0] | <0.001 |
| ➢ MAP < 55 mmHg | 0.0 [0.0-0.6] | 0.0 [0.0-0.0] | 0.027 |
| Patients with any major complication, N (%)* | 5 (26) | 2 (10) | 0.209 |
| ➢ Anastamotic leakage | 2 (11) | 1 (5) | 0.547 |
| ➢ Pulmonary edema | 0 (0) | 1 (5) | >0.999 |
| ➢ Reoperation | 3 (16) | 1 (5) | 0.290 |
| ➢ Bleeding | 1 (5) | 0 (0) | >0.999 |
| ➢ Atrial Fibrillation | 1 (5) | 0 (0) | >0.999 |
| Postoperative hemoglobin (g.dl−1) $ | 10.8 ± 1.9 | 11.3 ± 2.0 | 0.479 |
| Postoperative creatinine (mmol.l−1) $ | 76 [58 - 96] | 76 [61 - 99] | 0.540 |
| PACU-ICU length of stay (hours) | 9.0 [4.0-24.0] | 9.0 [5.0-24.0] | 0.988 |
| Hospital length of stay (days) | 9.0 [6.0-16.0] | 7.0 [5.0-16.0] | 0.609 |
Data are expressed as number and percentage (%) or median [25th -75th] percentiles. GDT: goal directed therapy; PACU: post-anesthesia care unit, ICU: intensive care unit.
*:
mortality at 30 days, stroke, renal replacement therapy and pulmonary embolism was 0% in both groups.
$:
postoperative hemoglobin and creatinine was measured on postoperative day 1 or 2.