. Author manuscript; available in PMC: 2022 Oct 7.

Published in final edited form as: J Theor Biol. 2021 Apr 27;526:110738. doi: 10.1016/j.jtbi.2021.110738

Table 1:

State variables for the model. Variables in both columns represent cells or mediators that diffuse between the two compartments.

Bloodstream	Lung	Description
	E_h	Healthy epithelial cells
	E_d	Damaged epithelial cells
	E_e	Dead epithelial cells/empty space
p_b	p	Pro-inflammatory mediators
a_b	a	Anti-inflammatory mediators
M_0b	M₀	Naive macrophages
M_1b	M₁	M1 pro-inflammatory macrophages
M_2b	M₂	M2 anti-inflammatory macrophages
N_0b		Unactivated neutrophils
N_b		Activated neutrophils
	N	Neutrophils
	AN	Apoptotic neutrophils
	R	Repair mediators