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. 2021 Jul 13;11:14396. doi: 10.1038/s41598-021-93831-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Genes derived from erythroid cells are highly expressed in SoJIA patients. (a) The gene expression of AHSP, HBD, and CA1 in peripheral blood mononuclear cells. Cells are obtained from patients with systemic lupus erythematosus, oligo/polyarticular juvenile idiopathic arthritis, bacteremia, Kawasaki disease, and systemic-onset juvenile idiopathic arthritis as well as healthy donors. (b) The mRNA levels of AHSP, HBD, and CA1 in whole blood and bone marrow mononuclear cells, along with purified populations of peripheral lymphocytes, monocytes, and CD71⁺ erythroid cells. Gene expression data are retrieved from the BioGPS database (http://biogps.org). The line indicates the average. Data are analyzed by the Mann–Whitney U test with Bonferroni correction. *P < 0.05; **P < 0.01; ***P < 0.001. SLE systemic lupus erythematosus, Oligo/poly JIA oligo/polyarticular juvenile idiopathic arthritis, KD Kawasaki disease, SoJIA systemic-onset juvenile idiopathic arthritis.