Table 3: Neuropsychiatric symptoms do not correlate with Lewy body score.
None of the neuropsychiatric symptoms correlated with Lewy body pathology in the locus coeruleus or the substantia nigra.
|
Lewy Body Regional Score
|
|||
| Neuropsychiatric symptom | Substantia nigra (n = 106) | Locus coeruleus (n = 86) | |
| 1 (n = 27) | 1 (n = 14) | ||
| 2 (n = 35) | 2 (n = 32) | ||
| 3 (n = 37) | 3 (n = 47) | ||
|
| |||
| Depression | N (%) | 11 (40.7%) | 7 (50%) |
| 13 (37.1%) | 13 (40.7%) | ||
| 22 (47.8%) | 19 (51.4%) | ||
|
| |||
| χ2 | 0.537 | 1.61 | |
| (df) | (2) | (2) | |
| P | 0.765† | 0.447† | |
|
| |||
| Adjusted P | 1.000a | 1.000a | |
|
| |||
| Anxiety | N (%) | 4 (14.8%) | 4 (28.6%) |
| 17 (53.1%) | 12 (34.3%) | ||
| 14 (30.4%) | 13 (35.1%) | ||
|
| |||
| χ2 | 9.98 | 0.204 | |
| (df) | (2) | (2) | |
| P | 0.007† | 0.903† | |
|
| |||
| Adjusted P | 0.042a | 1.000a | |
|
| |||
| Psychosis | N (%) | 14 (51.9%) | 6 (42.9%) |
| 18 (56.3%) | 17 (48.6%) | ||
| 20 (43.5%) | 15 (40.5%) | ||
|
| |||
| χ2 | 1.31 | 0.482 | |
| (df) | (2) | (2) | |
| P | 0.519† | 0.786† | |
| Adjusted P | 1.000a | 1.000a | |
|
| |||
†
Differences between groups were compared using Chi-Squared analysis
a
P-values adjusted to correct for multiple comparisons using the Holm method.