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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: J Voice. 2021 Jan 15;37(2):234–244. doi: 10.1016/j.jvoice.2020.12.029

Table 1.

Studies Demonstrating Temporal Relationships between Exposures to Airborne Stimuli and Development of Laryngeal Disorders Affecting Respiration.

Reference Study Design N Patient Descrintion Triggering
Stimulus
Exposure
Description
Diagnosis
Allan et al. (2006)46 Case report 1 49-year-old male firefighter Chlorine gas Single, accidental occupational exposure 15,000 gallons
Duration 6 hours
Vocal cord dysfunction
Bhargava et al. (2000)47 Case report 1 17-year-old male student athlete Swimming pool chlorine Chronic recreational exposure Paradoxical vocal cord dysfunction
Cummings et al. (2013)48 Case series 2 47-year-old female and 31-year-old female office workers Indoor mold growth in water-damaged buildings Chronic, accidental occupational exposure Vocal cord dysfunction
de la Hoz et al. (2008)49 Case series 10 6 male and 4 female 9/11 World Trade Center rescue workers and volunteers (age range 35-70 years) Variety of irritants and compounds from 9/11 World Trade Center disaster Chronic, accidental occupational exposure
Duration range 3-23 weeks
Vocal cord dysfunction
Galdi et al. (2005)50 Case report 1 47-year-old female nurse Glutaraldehyde Single occupational exposure
Duration 20-30 minutes
Vocal cord dysfunction
Gartner-Schmidt et al. (2008)51 Case report 1 53-year-old female Paint fumes Single occupational exposure Laryngeal hypersensitivity
Herin et al. (2012)52 Case report 1 38-year-old female hairdresser Bleaching agents Chronic occupational exposure Irritant-associated vocal cord dysfunction
Hoy et al. (2010)53 Case series 14 3 males and 11 females in manufacturing, sales, business, and construction (mean age 50.6 years) Perfumes
Cleaning agents
Paint fumes
Dust
Exhaust
Unspecified odors and fumes
Single and chronic occupational and recreational exposure Work-associated irritable larynx syndrome
Huggins et al. (2004)54 Case report 1 46-year-old female nurse Eucalyptus plant Chronic occupational exposure Vocal cord dysfunction
Marcinow et al. (2015)55 Case series 34 3 males and 31 females (age range 27-73 years) Not reported Single exposure Irritant-induced paradoxical vocal fold motion disorder
Munoz et al. (2007)56 Case report 1 26-year-old male carpenter Iroko and western red cedar wood dust Chronic occupational exposure Vocal cord dysfunction
Perkner et al. (1998)57 Case series 11 3 males and 8 females in manufacturing, housekeeping, health care, transportation, farming, clerical, safety inspection, and food service (mean age 45 years) Ammonia
Cleaning chemicals
Solder fumes
Smoke
Machine fluid
Ceiling tile dust
Unspecified odors
Single occupational and recreational exposure Irritant-associated vocal cord dysfunction
Reddy et al. (2004)58 Case report 1 25-year-old female Chlorine gas Single, accidental occupational exposure Vocal cord dysfunction
Tonini et al. (2009)59 Case report 1 45-year-old female nurse Isopropylic alcohol
Formaldehyde
Glutaraldehyde
Peracetic acid
Hydrogen peroxide
Sodium hypochlorite
Chronic occupational exposure Occupational irritant-induced vocal cord dysfunction
Weinberger et al. (2017)60 Case report 1 15-year-old female corn detasseler Sodium hypochlorite Cornfield Single occupational exposure Vocal cord dysfunction