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. 2021 Jun 30;9:652322. doi: 10.3389/fcell.2021.652322

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Copyright © 2021 Cui, Wang and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-630 was upregulated in OC. (A) Relationship between miRs and prognosis of OC was analyzed by Kaplan–Meier Plotter database; (B,C) OC cells with high metastasis and low metastasis were screened using Transwell assay; (D) Expressions of miR-141, miR-630, miR-106a, and miR-196b in SKOV3 and A2780 cells were detected using RT-qPCR; (E) morphology of NFs and CAFs was observed under the inverted phase contrast microscope; (F) levels of Vimentin, Cytokeratin and α-SMA in NFs and CAFs were detected using immunocytochemistry; (G) expressions of miR-630 and miR-196b in NFs and CAFs were detected using RT-qPCR. The experiment was repeated three times independently. Data are presented as mean ± standard deviation. Data in panels (B,C,D,G) were analyzed using one-way ANOVA, followed by Tukey’s multiple comparison test, ***p < 0.001, ^###p < 0.001.