. 2021 Jun 30;15:691222. doi: 10.3389/fnins.2021.691222

TABLE 1.

Data table.

		Aβarc	XJP-1		Donepezil		Rivastigmine		Galantamine		Memantine		XJP-1 (Memantine)		Donepezil (Memantine)

		Mean	Mean	P value vs. Aβarc	Mean	P value vs. Aβarc	Mean	P value vs. Aβarc	Mean	P value vs. Aβarc	Mean	P value vs. Aβarc	Mean	P value vs. Aβarc	Mean	P value vs. Aβarc
Lifespan assay		26.74	36.38	<0.0001	30.76	<0.0001	31.49	<0.0001	27.52	0.9994	32.61	0.0008	34.68	<0.0001	31.98	0.0005
Climbing assay	Day-2:	35.625	67.81	0.016	87.5	0.0003	87.083	0.0005	67.75	0.0511	67.868	0.041	37	0.932	72.6375	0.032
	Day-5:	34.3329	40.86	0.0724	75	0.006	66.75	0.0003	86.008	0.0088	79.86	0.0005	71.25	0.0088	70.5145	0.0003
	Day-7:	23.6085	50.08	0.04	38.5	0.028	56.223	0.0005	36.174	0.58	59.903	0.0006	68.26	0.0007	65.3487	0.0004
	Day-9:	12.5175	38.278	0.0014	27.1	0.77	31.25	0.042	21.166	0.61	27.487	0.059	36.93	0.0056	29.8625	0.0071
	Day-12:	9.5967	44.4	0.0008	29.5	0.019	24.438	0.58	31.832	0.0532	14.25	0.66	19.68	0.0839	10.685	0.7643
	Day-14:	6.925	31.05	0.022	33.6	0.0047	0	0.865	21.583	0.0799	23.369	0.062	44.35	0.0006	20.7625	0.0664
	Day-16:	3.6242	67.29	0.0002	49.7	0.0003	3.261	0.832	12.5	0.0527	23.369	0.052	11.84	0.054	0.06273	0.71
	Day-19:	4.886	15.418	0.032	18.7	0.012	2	0.75453	5.556	0.93	7.293	0.057	5.313	0.513	0.24573	0.361
	Day-21:	0.832	8.369	0.1734	8.13	0.0615	5.716	0.566	1.667	0.91	0	0.65	0	0.66	0	0.982
Amyloid spots (10 days)		987.5	362.3	0.0005	703.9	0.2691	773.1	0.5659	711.6	0.2961	639	0.1095	453	0.0035	886.3	0.984
Amyloid spots (20 days)		1137	383.5	<0.0001	390.5	<0.0001	525.7	0.0582	673.4	0.0657	373.5	<0.0001	520.2	0.0002	528	0.0096
MB + FBS amyloid spots (10 days)		465.3	196	0.0034	358.8	0.5605	325.4	0.2709	296	0.1204	307.6	0.1686	210.4	0.006	269.4	0.519
MB + FBS amyloid spots (20 days)		324.6	154.2	0.0029	133.2	0.0008	191.2	0.27	230.4	0.1934	133.2	0.0008	113.6	0.0002	164.4	0.0055
Medulla + OL (10 days)		459.7	219.2	0.0675	431	0.9996	308.4	0.2195	270.2	0.4465	285.2	0.2961	216.8	0.0635	331.8	0.6279
Medulla (OL (20 days)		607	321.2	0.0126	304.2	0.0075	419.4	0.1776	175	0.0014	253.8	<0.0001	202.4	0.0003	225	0.0006
Amyloid aggregation		93.85	23.52	0.0001	24.6	0.0002	56.12	0.0354	44.61	0.005	N/A	N/A	26.72	0.0002	33.72	0.0008

Comparison of mean and P-values of different treatment groups against the untreated Aβ_arc flies.