Table 2.
Univariate Logistic Regression Results of the Significant Risk Factors Reported in Table 1.
| Specification | Crude OR | Adjusted ORa | ||
|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Weight gain rate, g/d | ||||
| ≤ 12 | 4.55 (3.03–6.83) | <0.001 | 3.68 (2.11–6.40) | <0.001 |
| 12–18 | 5.14 (3.62–7.31) | <0.001 | 2.32 (1.48–3.64) | <0.001 |
| >18 | 1[Reference] | <0.001 | <0.001 | |
| FGR | 2.03 (1.32–3.10) | 0.001 | 2.52 (1.42–4.47) | 0.002 |
| Invasive mechanical ventilation | 10.78 (7.91–14.70) | <0.001 | 2.35 (1.60–3.44) | <0.001 |
| NT-proBNP ≥ 25,000 ng/L | 7.42 (5.52–9.97) | <0.001 | 2.18 (1.52–3.13) | <0.001 |
| SGA | 1.69 (1.25–2.29) | 0.001 | 1.80 (1.11–2.92) | 0.017 |
| Blood transfusion | 13.89 (8.71–22.16) | <0.001 | 1.79 (1.03–3.11) | 0.039 |
| BPD | 12.48 (9.11–17.10) | <0.001 | 1.67 (1.13–2.47) | 0.010 |
| NT-proBNP ≥ 20,000 ng/L | 5.80 (4.34–7.73) | <0.001 | 1.59 (1.12–2.28) | 0.010 |
| NT-proBNP ≥ 15,000 ng/L | 5.20 (3.92–6.88) | <0.001 | 1.49 (1.05–2.10) | 0.026 |
| NT-proBNP ≥ 10,000 ng/L | 4.93 (3.72–6.53) | <0.001 | 1.47 (1.04–2.07) | 0.030 |
| Apgar 5 min, score | ||||
| 1–3 | 2.20 (0.46–10.42) | 0.321 | 1.75 (0.29–10.70) | 0.546 |
| 4–7 | 5.56 (3.69–8.37) | <0.001 | 1.36 (0.81–2.28) | 0.245 |
| 8–10 | 1[Reference] | <0.001 | 0.433 | |
| Bad pregnancy or reproduction history | 1.55 (1.10–2.20) | 0.013 | 1.56 (0.99–2.45) | 0.055 |
| Asphyxia | 4.39 (3.30–5.85) | <0.001 | 1.39 (0.97–2.00) | 0.075 |
| Apnea | 3.77 (2.37–5.99) | <0.001 | 1.38 (0.79–2.41) | 0.263 |
| Coagulation dysfunction | 2.68 (1.99–3.60) | <0.001 | 1.34 (0.94–1.91) | 0.103 |
| Apgar 1 min, score | ||||
| 1–3 | 4.98 (2.64–9.38) | <0.001 | 1.32 (0.61–2.84) | 0.477 |
| 4–7 | 3.75 (2.80–5.03) | <0.001 | 1.17 (0.81–1.70) | 0.398 |
| 8–10 | 1[Reference] | <0.001 | 0.597 | |
| Amniotic fluid pollution | 2.02 (1.48–2.76) | <0.001 | 1.29 (0.87–1.89) | 0.201 |
| Pulmonary surfactant therapy | 9.75 (7.06–13.45) | <0.001 | 1.21 (0.79–1.84) | 0.385 |
| RDS | 9.68 (6.37–14.69) | <0.001 | 1.11 (0.66–1.86) | 0.692 |
| Cesarean section | 0.43 (0.31–0.59) | <0.001 | 1.04 (0.68–1.61) | 0.844 |
| Cerebral hemorrhage | 1.85 (1.37–2.49) | <0.001 | 1.02 (0.71–1.46) | 0.926 |
| Intrauterine asphyxia | 3.05 (1.33–7.01) | 0.008 | 0.68 (0.26–1.74) | 0.417 |
CI, confidence interval; OR, odds ratio; FGR, fetal growth restriction; SGA, small for gestational age; BPD, bronchopulmonary dysplasia; RDS, respiratory distress syndrome.
a
All analyses only adjusted for known risk factors: GA, SGA. The analysis results are ranked according to the adjusted statistical significance.