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. 2021 Jun 30;12:681867. doi: 10.3389/fgene.2021.681867

TABLE 3.

The relationship between the signature and clinical features.

Clinical feature Group n Mean SD t P value Adjusted P value
Age ≥60 54 1.489 1.152 2.054 0.043* 0.258
<60 73 1.113 0.809
Gender Female 57 1.25 1.05 –0.226 0.821 1.000
Male 70 1.291 0.933
Blast cell High 65 1.312 0.902 0.453 0.652 1.000
Low 62 1.232 1.068
Bone marrow blast cell High 64 1.351 1.094 0.907 0.366 1.000
Low 63 1.193 0.858
Hemoglobin High 102 1.229 0.882 –0.794 0.434 1.000
Low 25 1.451 1.326
Leukocyte High 64 1.47 1.16 2.326 0.022* 0.154
Low 63 1.072 0.718
FAB M3 13 0.457 0.341 –6.863 0.000*** 0.000
non-M3 114 1.366 0.99
Cytogenetics risk Favorable + Normal 100 1.266 1.015 –0.164 0.870 1.000
Poor 27 1.298 0.874

*p < 0.05, ***p < 0.001.