FIGURE 3.

Knock‐down of METTL16 inhibits the proliferation of GC cells in vitro. (A) The mRNA expression of METTL16 in three GC cell lines (AGS, MGC803 and SNU719) after treated with METTL16 shRNA lentivirus. (B) The protein expression of METTL16 in three GC cell lines after treated with METTL16 shRNA lentivirus. (C) Knock‐down of METTL16 can effectively inhibit cell growth in AGS, MGC803 and SNU719 cells. (D and E) Colony formation of AGS, MGC803 and SNU719 cells after transfection of shMETTL16 or shNC. All experiments were performed in triplicate. *P < .05, **P < .01