FIGURE 7.

Effect of MT‐TG on cardiac Akt2‐mediated glucose metabolism in Akt2‐KO mice. Heart PAS staining (A), red spots mean glycogen. Cardiac expression and its phosphorylation of AS160 (B), HKII (C), PFKFB2 (D) and ERK1/2 (E) were detected by Western blot. Data are presented as mean ± SD (WT: n = 9 in male; n = 6 in female; MT‐TG: n = 8 in male; n = 5 in female; Akt2‐KO: n = 8 in male; n = 8 in female; MT‐TG/Akt2‐KO: n = 9 in male; n = 9 in female). Quantitation plots are expressed as fold WT control. *P <.05 vs the WT; **P <.01 vs the WT; &P <.05 vs Akt2‐KO; &&P <.01 vs Akt2‐KO