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. 2021 Mar 31;23(1):28–36. doi: 10.18176/resp.00028

Table 4. Therapeutic options for treating latent tuberculosis infection.

Drugs Duration Interval HIV classification (-) HIV classification (+)
Isoniazid 9 months Daily A (II) A (II)
Isoniazid 6 months Daily B (I) C (I)
Rifampicin + Isoniazid 3 months Daily A (II) A (II)
Rifampicin 4 months Daily B (II) B (III)

Note. Weight of recommendation: A: preferable; B: acceptable alternative; C: only use when A and B are not possible. Quality of evidence: I: evidence from random clinical assays; II: evidence from non-random clinical assays. III: expert opinion. HIV: human immunodeficiency virus.