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. 2021 Jul 14;22:449. doi: 10.1186/s13063-021-05410-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Overview of the PolyPrime study and process evaluation activities. *The follow-up time points for the control arm will be based on the average length of time from the completion of baseline data collection to 6 and 9 months post initial medication review in the intervention arm. **Process evaluation activities—counts of GP viewing online video, weekly practice meetings to discuss medication reviews, scheduling of appointments and prompts given to GPs by practice staff to conduct medication reviews. ***Process evaluation activities—semi-structured interviews with GPs and practice staff after medication review 2. NI-Northern Ireland; ROI Republic of Ireland